Effect of Intravenous Iron Sucrose on Exercise Tolerance in Anemic and Nonanemic Patients With Symptomatic Chronic Heart Failure and Iron Deficiency
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چکیده
Methods We randomized 35 patients with CHF (age 64 13 years, peak oxygen consumption [pVO2] 14.0 2.7 ml/kg/ min) to 16 weeks of intravenous iron (200 mg weekly until ferritin 500 ng/ml, 200 mg monthly thereafter) or no treatment in a 2:1 ratio. Ferritin was required to be 100 ng/ml or ferritin 100 to 300 ng/ml with transferrin saturation 20%. Patients were stratified according to hemoglobin levels ( 12.5 g/dl [anemic group] vs. 12.5 to 14.5 g/dl [nonanemic group]). The observer-blinded primary end point was the change in absolute pVO2.
منابع مشابه
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تاریخ انتشار 2007